Ironstrength, the Doctor's Total-Body Exercise Routine - New York Times video

Dr. Jordan Metzl is a sports medicine physician who developed an extreme total-body workout routine called Ironstrength. He now teaches free exercise classes all around New York City. Produced by: Colin Archdeacon.

Myelodysplastic Syndromes / Myeloproliferative Disorders

What are myelodysplastic syndromes?

Myelodysplastic syndromes are clonal marrow stem-cell disorders, characterized by ineffective hemopoiesis leading to blood cytopenias, and by progression to acute myeloid leukemia in a third of patients.

Who is affected?

15% of cases occur after chemotherapy or radiotherapy for a previous cancer. The syndromes are most common in elderly people.

What is the cause?

The pathophysiology involves cytogenetic changes with or without gene mutations and widespread gene hypermethylation at advanced stages.

What are the symptoms?

Clinical manifestations result from cytopenias (anemia, infection, and bleeding).

How to make the diagnosis?

Diagnosis is based on examination of blood and bone marrow showing blood cytopenias and hypercellular marrow with dysplasia, with or without excess of blasts. Prognosis depends largely on the marrow blast percentage, number and extent of cytopenias, and cytogenetic abnormalities.

What is the treatment?

Treatment of patients with lower-risk myelodysplastic syndromes, especially for anaemia, includes growth factors, lenalidomide, and transfusions.

Treatment of higher-risk patients is with hypomethylating agents and, whenever possible, allogeneic stem-cell transplantation.

In this first video in the series, Myeloproliferative Neoplasms 2015 - Mayo Clinic, Ruben Mesa, M.D., professor and hematologist at Mayo Clinic in Arizona, discusses the treatment and management of myeloproliferative neoplasms as well as shares highlights from the 56th Annual American Society of Hematology (ASH) meeting in San Francisco, December 2014.



Here is the complete playlist:

https://www.youtube.com/playlist?list=PLSWR1ylG_6JZKr0ChD4N_8MJ3g3FnF08S

References:

Myelodysplastic syndromes : The Lancet http://buff.ly/VwiRor

Keratitis and Contact Lens Use - CDC video

Misuse of contact lenses (wearing them too long, not cleaning them properly) causes 1 million eye infections/yr in US. "Contact lenses offer many benefits, but they are not risk-free. Keratitis can be a scary infection, but it is preventable if people follow healthy habits and take care of their eyes and their lenses". Some bad habits, such as sleeping with contact lenses, failing to clean and replace lens solution frequently, and letting contact lenses get wet while swimming or in the shower, greatly raises the risk for keratitis. People who wear their contact lenses overnight are more than 20 times more likely to get keratitis. http://buff.ly/1xw4iSn

A few basic 'contact lens hygiene' measures can keep patients free of keratitis -- Keratitis and Contact Lens Use - CDC, YouTube:


Tracking Sleep With Wearables Literally Changed My Life - The Medical Futurist

From Bertalan Mesko: "I use wearable gadgets to measure the quality of my sleep and as some of the subscribers asked me how I do that in details step by step, I thought I would share the whole process and my methods in one video. I hope you will find it useful."

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